public anal danyela alves

A Randomized Multicenter Trial. Assessment of early continence after reconstruction of the periprostatic tissues in patients undergoing computer assisted robotic prostatectomy: The survival impact of the choice of surgical procedure after ipsilateral breast cancer recurrence.

A Randomized Controlled Trial. A case control study. Expanding the role of hepatic resection in the age of multimodal therapy. Are We Approaching an Answer? Efficacy and Toxicity Data from a Retrospective Study. Central Venous Catheters access, care, diagnosis and therapy of complications. ESMO clinical recommendations for diagnosis, treatment and follow-up.

Workflow della Ricerca 2. A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM, a novel Aurora kinase inhibitor. Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization. Epigenetic therapies in haematological malignancies: Epigenomic profiling of cancer cells. Ethics report on interspecies somatic cell nuclear transfer research. Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells.

Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation. K-ras status in squamous cell anal carcinoma SCC: Mitochondria and vascular pathology.

Mitochondrial pathways for ROS formation and myocardial injury: Protein phosphatases take the mitotic stage. Systems-wide analysis of a phosphatase knock down by quantitative proteomics and phosphoproteomics.

Tandem repeats modify the structure of human genes hosted in segmental duplications. The future therapeutic potential of histone demethylases: The gene prognosis-signature predicts disease outcome in breast cancer patients with positive lymph nodes in an independent validation study.

Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab. What to do with the Grail now that we have it? A novel t 7;13 p12;q33 approximately q34 in AML-M2. Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma MPM cells.

Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks. Fragment-based identification of Hsp90 inhibitors. Heat-shock factor 1 controls genome-wide acetylation in heat-shocked cells.

Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer. Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Isolation and characterization of DUSP11, a novel p53 target gene.

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. P66Shc signals to age. Rai acts as a negative regulator of autoimmunity by inhibiting antigen receptor signaling and lymphocyte activation. The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts.

The life and miracles of kinetochores. Two modes of transcriptional activation at native promoters by NF-kappaB p When sirtuins and NF-kappaB collide. Awaking stem cells from dormancy: Fractal growth of tumors and other cellular populations: Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells.

Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD cell population with intrinsic resistance to imatinib. Pathological definition of triple negative breast cancer. Redundant function of retinoic acid receptor isoforms in leukemogenesis unravels a prominent function of genome topology and architecture in the selection of mutagenic events in cancer.

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. A reevaluation of the clinical significance of histological subtyping of non-small-cell lung carcinoma: A risk score to predict disease-free survival in patients not achieving a pathological complete remission after preoperative chemotherapy for breast cancer.

Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor. Are surveillance procedures of clinical benefit for patients treated for ovarian cancer? Biomarkers for risk assessment and prevention of breast cancer. Central nervous system metastases in a cohort of metastatic breast cancer patients treated with trastuzumab. Circulating melanoma cells and distant metastasis-free survival in stage III melanoma patients with or without adjuvant interferon treatment EORTC side study.

Communication skills and raising awareness in clinical practice: Distribution of human papillomavirus genotypes in invasive cervical cancer in Italy: Epidemiology of pancreatic cancer: Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor BDNF.

For the sake of clarity about pT4 category of colorectal cancer. Hepatitis C virus genotype 1b as a risk factor for hepatocellular carcinoma development: Improved histologic and clinicopathologic criteria for prognostic evaluation of pancreatic endocrine tumors. Increasing steroid hormone receptors expression defines breast cancer subtypes non responsive to preoperative chemotherapy.

Information-related changes in contact patterns may trigger oscillations in the endemic prevalence of infectious diseases. Integrating molecular profiling, histological type and other variables: Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: Lack of prognostic significance of "classic" lobular breast carcinoma: Natural History of Acute Pancreatitis: Review and meta-analysis on Vitamin D Receptor polymorphisms and cancer risk.

Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy. The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells. The changing character of acute pancreatitis: The Gene expression Grade Index: The Harmless Acute Pancreatitis Score: Tumor deposits are encountered in advanced colorectal cancer and other adenocarcinomas: Which factors affect pulmonary function after lung metastasectomy?

Before they were gut dendritic cells. Best choice of central venous insertion site for the prevention of catheter-related complications in adult patients who need cancer therapy: Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG trial.

Bone Quality Test BQT scores of fingernails in postmenopausal patients treated with adjuvant letrozole or tamoxifen for early breast cancer.

Clinical and pharmacological phase I evaluation of exherin ADH-1 , a selective anti n-cadherin peptide in patients with n-cadherin expressing solid tumours. Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: Dendritic cells in intestinal homeostasis and disease.

Erlotinib combined with cyclosporine in a liver-transplant recipient with epidermal growth factor receptor-mutated non-small cell lung cancer. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. Gemcitabine and pemetrexed combination: HSPPC vaccine in metastatic melanoma patients: Immunizing against breast cancer: Infusional fluorouracil, epirubicin, and cisplatin followed by weekly paclitaxel plus bevacizumab in locally advanced breast cancer with unfavorable prognostic features.

International guidelines for management of metastatic breast cancer: Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning. Investigations after adjuvant therapy. Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? Is chemotherapy necessary for premenopausal women with lower-risk node-positive, endocrine responsive breast cancer?

Is there a role for 'modified VAD' in the treatment of multiple myeloma? Minimal axillary lymph node involvement in breast cancer has different prognostic implications according to the staging procedure. Molecular target therapy for gastroenteropancreatic endocrine tumours: Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: Patterns of recurrence of early breast cancer according to estrogen receptor status: Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours.

Phase I clinical and pharmacokinetic study of trabectedin and doxorubicin in advanced soft tissue sarcoma and breast cancer. Preoperative chemo- and endocrine therapy. Evidence of a cold immunoglobulin M autoantibody against kD platelet glycoprotein in a case of EDTA-dependent pseudothrombocytopenia.

Preliminary molecular analysis of a case of feline mucopolysaccharidosis VI. Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.

In vivo accumulation of 8-hydroxy-2'-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families. In vitro correction of iduronatesulfatase deficiency by adenovirus-mediated gene transfer. Animal models for lysosomal storage diseases: Cell-to-cell contact between normal fibroblasts and lymphoblasts deficient in lysosomal enzymes. Biochemical diagnosis of mucopolysaccharidoses: Identification of molecular defects in Italian Sanfilippo A patients including 13 novel mutations.

Isolation of a cDNA encoding a metal response element binding protein using a novel expression cloning procedure: Two novel R C; TD and two repeat missense mutations in the protein C gene associated with venous thrombosis in six kindreds.

A nuclear factor binds to the metal regulatory elements of the mouse gene encoding metallothionein-I. Rational design of true hirudin mimetics: Immunocytochemical analysis of the transfer of vesicular stomatitis virus G glycoprotein from the intermediate compartment to the Golgi complex.

Morphological analysis of the transfer of VSV ts G glycoprotein from the endoplasmic reticulum to the intermediate compartment in vero cells.

Surface distribution and partition during freeze-fracture of CD8 antigens on human lymphocytes and on epithelial transfected cells. Effect of rat liver cytosolic enzymes and cofactors on mutagenicity of 1-aminonitropyrene. Interactions of nuclear proteins from uninduced, induced and superinduced HeLa cells with metal regulatory elements MRE3 and 4 of the human metallothionein IIa-encoding gene.

Synthesis of rhodanese in Hep 3B cells. The iduronate sulfatase gene: Post-translational processing of an O-glycosylated protein, the human CD8 glycoprotein, during the intracellular transport to the plasma membrane. Biosynthesis and oligosaccharide structure of human CD8 glycoprotein expressed in a rat epithelial cell line.

Dynamics of transmembrane proteins during Sindbis virus budding. Collagen expression in quail embryo chondrocytes treated with retinoic acid. Alpha 2 I collagen gene expression is up-regulated in quail chondrocytes pretreated with retinoic acid. Enhancement of tissue lipoperoxidation in propanil-treated rats.

Amino acid sequence and molecular modelling of glycoprotein IIb-IIIa and fibronectin receptor iso-antagonists from Trimeresurus elegans venom. Glycosylation and maturation rate of membrane and secretory forms of human CD8 alpha glycoprotein. Implications in the activation of T-lymphocytes. Sanfilippo syndrome type D in two adolescent sisters.

Echistatin inhibits the adhesion of murine melanoma cells to extracellular matrix components. Echistatin induces decrease of ppFAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells.

Echistatin inhibits pp72syk and ppFAK phosphorylation in fibrinogen-adherent platelets. Anchorage-dependent surface distribution and partition during freeze-fracture of viral transmembrane glycoproteins.

Effect of ATP depletion and DTT on the transport of membrane proteins from the endoplasmic reticulum and the intermediate compartment to the Golgi complex. Opposite polarity of virus budding and of viral envelope glycoprotein distribution in epithelial cells derived from different tissues. The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode.

Species-dependent specificity of platelet aggregation inhibitors from snake venoms. The carcinogenic mycotoxin fumonisin B1 inhibits integrin-mediated cell-matrix adhesion. From natural to synthetic multisite thrombin inhibitors. Prenatal diagnosis of Sanfilippo type A syndrome in a family with S66W mutant allele. Bone marrow transplantation in a Hunter patient with PH mutation. Cell fractionation analysis of human CD8 glycoprotein transport between endoplasmic reticulum, intermediate compartment and Golgi complex in tissue culture.

Tissue-transglutaminase expression in quail epiphyseal chondrocytes. A chimeric elongation factor containing the putative guanine nucleotide binding domain of archaeal EF-1 alpha and the M and C domains of eubacterial E. The interaction between the archaeal elongation factor 1a and its nucleotide exchange factor 1b. Regulation of cell survival in CDinduced T cell apoptosis: CD40 and B chronic lymphocytic leukemia cell response to fluderabine: Sequence and analysis of chromosome 4 of the plant Arabidopsis Thaliana.

Changes in tissue transglutaminase activity and expression during retinoic acid-induced growth arrest and apoptosis in primary cultures of human epithelial prostate cells. Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein. A novel case of multiple endocrine neoplasia type 2 associated with two de novo mutations of the RET protooncogene.

Pro12Ala substitution in the peroxisome proliferator activated receptor-gamma 2 is not associated with type 2 diabetes. The type and the localization of cAMP-dependent protin kinase regulate trasmission of cAMP signals to the nucleus in cortical and cerebellar granule.

Thrombin mutants with altered enzymatic activity have an altered mitogenic activity on NIH3T3 cells and are inefficient modulators of rat cortical astrocyte stellation. A case of discordance between genotype and phenotype in a malignant hyperthemia family. IgA antibodies to tissue transglutaminase: Efficiency of two different nine-loci short tandem repeat systems for DNA typing purposes. Novel six-nucleotide deletion in the hepatic fructose-1,6-bisphosphate aldolase gene in a patient with hereditary fructose intolerance and enzyme structure-function implications.

Serum gamma-glutamyltransferase isoform complexed to LDL in the diagnosis of small hepatocellular carcinoma. Detection of five rare cystic fibrosis mutations peculiar to Southern Italy: Familial adenomatous polyposis coli: PKC-dependent phosphorylation of the p97 repressor regulates the transcription of aldolase A L-type promoter. Stem cell factor is localized in released form, and cleaved by human mast cells. Dual control of C-reactive protein gene expression by interleukin-1 and interleukin Comparison of seven serum assays on four automatic analysers.

Characterization of the induction of rat hepatic microsomal drug-metabolizing enzymes by 1-nitropyrene metabolites, 1-aminopyrene and N-acetylaminopyrene. Palmitylation of viral membrane glycoproteins takes place after exit from the Endoplasmic Reticulum. Biosynthesis, membrane translocation, and surface expression of sindbis virus E1 glycoprotein.

Biochemical diagnosis of Hunter syndrome on Epstein-Barr virus transformed lymphoblastoid cell lines. Mapping of the gene TCF2 coding for the transcription factor LFB3 to human chromosome 17 by polymerase chain reaction.

Transcription of the promoter of the rat NF-l gene depends un the integrity of an Sp1 recognition site. Extinction of retinol-binding protein gene expression in somatic cell-hybrids: Identification of the target sequences. Regulation of the human C-reactive protein gene, a major marker of inflammation and cancer. Promoters and inhibitors of calcium urolithiasis in children. Metabolic activation of dinitropyrenes by human liver fractions.

Long term antihypertensive effect of magnesium supplementation in primary hypertension. Single-step purification and structural characterization of human interleukin-6 produced in Escherichia coli from a T7 RNA polymerase expression vector.

Regulation and expression of type V Tartrate-resistant acid phosphatase in human mononuclear phagocytes. Correlates of high-density lipoprotein cholesterol in a sample of healthy workers. Serum selenium and coronary heart disease risk factors in southern Italian men. Early macrophage infiltration in Mice treated with low-dose streptozocin decreases islet suproxide dismutase levels: Superoxide dismutase in low-dose-streptozocin-treated mice.

Vitamin A intake and in vivo expression of the genes involved in retinol transport. Biologically active recombinant prothrombin and antithrombin III expressed in a human hepatoma vaccinia virus system. Reversible inhibition of thyroid-specific trans-acting factor by Ras. Effect of avarol, avarone and nine their natural and synthetic derivatives on drug-metabolizing enzymes.

Tubular function by lithium clearance, plasma amino acids and hormones following a meat meal in childhood. Expression of type X collagen is transiently stimulated in redifferentiating chondrocytes pretreated with retinoic acid. Identification of regulatory residues of the yeast adenylyl cyclase. Role of glycine as a pivot point during the transition from the inactive to the active form of the yeast Ras2 protein. A consensus view on the use of immunodeficient mice in immunology and oncology.

Extinction of a-1 antitrypsin gene expression in somatic cell hybrids: Control of human coagulation by recombinant serine proteases. Blood clotting is activated by recombinant factor XII deleted of five regulatory domains. Per-rectal portal scintigraphy with technetiumm pertechnetate for the early diagnosis of cirrhosis in patients with chronic hepatitis.

Transcription factors of liver-specific genes. Calcium and blood pressure in a sample of male workers. Hemodialysis related induction of interleukin-6 production by peripheral blood mononuclear cells. Idiopathic neonatal hepatitis in one DNA fingerprint identical twin.

Effect of avarol and avarone on in vitro-induced microsomal lipid peroxidation. Glucagon-independent renal hyperaemia and hyperfiltration after an oral protein load in child a liver cirrhosis. Renal handling of sodium after an oral protein load in adult humans.

Long-term magnesium supplementation in essential hypertension. Structural characterization of a biologically active human lipocortin 1 expressed in Escherichia coli. Can overnight urine replace hour urine collection to measure urinary calcium in epidemiologic studies? Human L7a ribosomal protein: Cellular retinoic-acid-binding-protein mRNA expression in the cells of the rat seminiferous tubules and their regulation by retinoids.

Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression. Diagnostic and discriminatory efficiency of eight serum modified nucleosides in HIV infection and in AT-Risk subjects. A method for the assay of phosphatidylinositol-specific phospholipase D activity in serum. Identification of a binding site for the human immunodeficiency virus type I nucleocapsid protein.

Extinction of insulin-like growth factor II gene expression in intratypic hibrids of rat liver cells. Nucleotide sequence and molecular evolution of the gene coding for glyceraldehydephosphate dehydrogenase in the thermoacidophilic archaebacterium Sulfolohus solfataricus. T cell growth-promoting activity of JFN-y: Rapid and efficient resolution of parentage by amplification of short tandem rcpeats. High-resolution solution structure of the oligomerization domain of p53 by multidimensional NMR.

The carboxy-terminal serine phosphorylation site of human p53 Fis not required for wild-type activities. Lipids of human gastric mucosa: An increase in superoxide dismutase counteracts islet vascular alterations in low-dose streptozocin-treated mice. Arylation of sulfhydryl groups in vitro by the naturally occurring sesquiterpenoid benzoquinone avarone. Cristallization of a hyperthermophilic archaeal elongation factor 1a.

The effects of intra-articular administration of hyaluronic acid on osteoarthritis of the Knee: Differential regulation of the expression of interleukin-2 receptor y-chain during the in vitro differentiation of human myeloid cells.

Oxidative structural modifications of low density lipoprotein in homozygous familial hypercholesterolemia. Direct detection of proviral-gag-segment of human immunodeficiency virus in peripheral blood lymphocytes by colorimetric PCR assay as a Clinical Laboratory tool applied to different at-risk populations. Superoxide dismutase in the nonobese diabetic NOD mouse: Detection of an antigenic marker expressed by peripheral blood monocytes and platelets by a new monoclonal antibody, UN8.

The role of cell adhesion in Retinoic acid-induced modulation of chondrocytes phenotype. Interaction between archaeal elongation factors lb and la. A mutation in the RET proto-oncogene in Hirschsprung's disease affects the tyrosine kinase activity associated with multiple endocrine neoplasia type 2A and 2B. Complete phenotypic and genotypic lineage switch in a Philadelphia chromosome-positive acute lymphoblastic leukemia. Inhibition of human platelet adhesion to immobilized extracellular matrix components by disintegrins.

Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction. Aspartate aminotransferase from the thermophilic bacterium Thermus aquaticus YT Functional characterisation and stability. The effect of low density lipoprotein fatty acid compoosition on copper-induced peroxidation: Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli.

Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle-and developmentally regulated promoter. Proteolysis of the exodomain of recombinant protease-activated receptors: Oxalomalate, a competitive inhibitor of aconitase, modulates the RNA-binding activity of iron-regulatory proteins. Over expression of H ferritin and upregulation of iron regulatory protein genes during differentiation of 3T3-L1 pre-adipocytes.

Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis. Protein engineering on enzymes of the peptide elongation cycle in Sulfolobus solfataricus. Discrimination between Celiac and other gastrointestial disorders in childhood by rapid human lymphocyte antigen typing. Germime and somatic mutations of the RET proto-oncogene in apparently sporadic medullary thyroid carcinomas. Mutations in the extracellular domain cause RET loss of function by a dominant negative mechanism.

Echistatin inhibits Lewis lung carcinoma cell-matrix adhesion in vitro and experimental metastasis in vivo. Functional characterization of elegantin isoform, RGD-polypeptides isolated from the venom of Trimeresurus elegans. Stable expression and purification of a secreted human recombinant prethrombin-2 and its activation to thrombin.

Mutations among Italian Mucopolysaccharidosis type I patients. Detection of four novel mutations in the iduronatesulfatase gene. Two novel mutations of the arylsulfatase B gene in two Italian patients with severe form of mucopolysaccharidosis. Retynil esters hydrolysis and retinol efflux from BFC-1beta adipocytes. Retinoic acid receptors a, b and g and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer. A novel point mutation in the intracellular domain of the RET proto-oncogene in a family with medullary thyroid carcinoma.

Identification of two mutations within the transglutaminase 1 gene in patients with lamellar ichthyosis. Microsatellite instability in patients with early onset of colorectal cancer.

Constitutive and IL-6 induced nuclear factors that interact with the human C-reactive protein promoter. Internal deletion of human interleukin Internal deletion of amino acids of human interleukin-6 IL-6 differentially affect bioactivity and folding of the protein.

Involvement of the Arg in the active site of human IL Synergistic stimulation of interleukin-6 release and gene expression by phorbol esters and interleukin-1 in rat cortical astrocytes: Two types of zinc fingers are required for dimerization of the serendipity delta transcriptional activator.

Transcriptional control of gene expression in hepatic cells. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Psychrophilic elongation factor Tu from the Antarctic Moraxella sp. Expression of five iduronatesulfatase site-directed mutations. Echistatin inhibits ppFAK autophosphorylation paxillin, phosphorylation and ppFAK-paxillin interaction in fibronectin-adherent melanoma cells.

Molecular defects in the alfa-N-acetylglucosaminidase gene in Italian Sanfilippo type B patients. The beta-amyloid precursor protein APP functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation.

Identification of a novel mutation in the ryanodine receptor gene RYR1 in a malignant hyperthermia italian family. Functional and molecular modelling studies of two hereditary fructose intolerance-causing mutations at arginine in human liver aldolase. Quantitative analysis of aldolase A mRNA in liver discriminates between hepatocellular carcinoma and cirrhosis. Prenatal diagnosis of cystic fibrosis: Genetic history of cystic fibrosis mutations in Italy.

Evidence for a recessive inheritance of Turcot's syndrome caused by a compound heterozygous mutation within the PMS2 gene. H2O2 activity on platelet adhesion to fibrinogen and protein tyrosine phosphorylation. Immobilised echistatin promotes platelet adhesion and protein tyrosine phosphorylation. Retinol and retinol-binding protein: Identification of a novel retinoic acid response element in the promoter region of the retinol-binding protein gene.

Retinoids regulate expression of the retinol-binding protein in hepathoma cells in culture. The archaeal elongation factor 1alpha bound to GTP forms a ternary complex with eubacterial and eukaryal aminoacyl-tRNA. A new determinant of endoplasmic reticulum localization is contained in the juxtamembrane region of hepatitis C virus glycoprotein E1.

Zinc transport and metallothionein secretion in the intestinal human cell line Caco Sequence polymorphisms in the apo a gene associated with specific levels of Lp a in plasma. Rapid genotyping of the low density lipoprotein receptor knock-out mice using a polymerase chain reaction method. Sequence microheterogeneity in the apolipoprotein a gene repeats and the relationship to plasma Lp a levels.

Plasma lipoprotein a levels in subjects attending a metabolic ward. Discrimination between individuals with and without a history of ischemic stroke. Thrombogenic mechanisms in hyperhomocysteinemia. A simple and rapid purification procedure minimizes spontaneous oxidative modifications of low density lipoprotein and lipoprotein a. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.

Influence of cardiovascular risk factors between angiotensin converting enzyme-gene polymorphism and blood pressure in arterial hypertension. Retinoblastoma protein dephosphorylation is an early event of cellular response to prooxidant conditions. Type V Acid Phosphatase: Macroenzyme investigation and monitoring in children with persistent increase of aspartate aminotransferase of unexplained origin.

Occurrence of the same peroxidative compounds in low density lipoprotein and in atherosclerotic lesions from a homozygous familial hypercholesterolemic patient: Automated enzymatic determination of urinary nitrates excrection: Increased low-density lipoprotein peroxidation in elderly men. Comparative bioavailability of two sertraline tablet formulations in healthy human volunteers after a single dose administration.

Randomized, double-blind, placebo-controlled study of arginine supplemetation in chronic renal failure. Biochemical characterization of two crotamine isoforms isolated by a single step RP-HPLC from Crotalus durissus terrificus South American rattlesnake venom and their action on insulin secrection by pancreatic islets.

Serum lipids and apolipoproteins in children with Smith-Lemli-Opitz syndrome. Smith-Lemli-Opitz syndrome with extremely low plasma cholesterol. Progress in Arabidopsis genome sequencing and functional genomics. Phenylmethanesulfonyl fluoride inactivates an archaeal superoxide dismutase by chemical modification of a specific tyrosine residue Cloning, sequencing and expression of the gene coding for Sulfolobus solfataricus superoxide dismutase.

Liver expression in cystic fibrosis could be modulated by genetic factors different from the cystic fibrosis transmembrane regulator genotype. The molecular basis of familial adenomatous polyposis in 20 families from Campania: The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene.

Transglutaminase 1 gene mutations in italian patients with autosomal recessive lamellar ichthyosis. The crystal structure of Sulfolobus solfataricus elongation factor 1 alpha in complex with GDP reveals novel features in nucleotide binding and exchange. Multivariate discriminant function based on six biochemical markers in blood can predict the cirrhotic evolution of chronic hepatitis. Site-specific atherosclerotic plaques in the carotid arteries of middle-aged women from southern Italy: Salts induce structural changes in elongation factor 1 alpha from the hyperthermophilic archaeon Sulfolobus solfataricus: Phenotype-Genotype correlations in an extended family with adenomatous coli and an unusual APC gene mutation.

Protection of rhesus macaques against disease progression from pathogenic SHIV Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein. Predictive value of Epstein-Barr virus genome copy number and BZLF1 expression in blood lymphocytes of transplant recipients at risk for lymphoproliferative disease. Extraneurologic symptoms as presenting signs of Sanfilippo disease. The effect of four mutations on the expression of iduronatesulfatase in mucopolysaccharidosis type II.

The human homologue of the mouse Surf5 gene encodes multiple alternatively spliced transcripts. Generation of helper-dependent adenoviral vectors by homologous recombination. An Alternative model of H ferritin promoter transactivation by c-Jun. A continuous line of chick embryo cells derived from a chondrocyte culture transformed with RSV.

The podosomes of RSV transformed chondrocytes show a peculiar ultrastructural organization. Association of impaired glucose homeostasis with preclinical carotid atherosclerosis in women: The first large population based twin study of coeliac disease.

Serum oxidative and antioxidant parameters in a group of Italian patients with age-related maculopathy. Stage-specific gene expression in early differentiating oligodendrocytes. Protein synthesis in the extreme thermophilic archaeon Sulfolobus solfataricus: Measurement of spleen volume by ultrasound scanning in patients with thrombocytosis: Novel deletion at the M and P promoters of the human dystrophin gene associated with a Duchenne muscular dystrophy.

In vitro acquired cellular senescence and aging-specific phenotype can be distinguished on the basis of specific mRNA expression. Genotype-Phenotype correlation in Cystic Fibrosis: The Role of Modifier Genes.

Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Dietary and circulating antioxidant vitamins in relation to carotid plaques in middle-aged women. Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance. Correction of mucopolysaccharidosis type IIIB fibroblasts by lentiviral vector-mediated gene transfer. In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors. Identification of tissue transglutaminase-reactive lysine residues in glyceraldehydephosphate dehydrogenase.

Folding and oxidation of the antibody domain CH3. Extended interactions with prothrombinase enforce affinity and specificity for its macromolecular substrate. Oxidative stress and neuroAIDS: Structural characterization of transglutaminase-catalyzed cross-linking between glyceraldehyde 3-phosphate dehydrogenase and polyglutamine repeats. Pancreatic-type ribonuclease 1 gene duplications in rat species.

Molecular Diagnosis of Cystic Fibrosis: Cloning, expression and evolution of the gene encoding the elongation factor 1a from a low thermophilic Sulfolobus solfataricus strain. Differential distribution of aldolase A and C in the human central nervous system. Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.

Recent advances in the diagnosis of malignant hyperthermia susceptibility: How confident can we be of genetic testing? Analysis of transglutaminase protein substrates by functional proteomics. Cell-matrix interactions and the control of cell shape and differentiation in primary cultures of avian chondrocytes.

Altered expression of integrins in RSV-transformed chick epiphyseal chondrocytes. Protein kinase B activation by reactive oxigen species is independent of tyrosine kinase receptor phosphorylation and requires Src activity. Proteomics identification of Acyl-acceptor and Acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line.

Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic replicons. KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment and Golgi complex. BAG3 protein controls B-chronic lymphocytic leukemia cell apoptosis.

Carcinoembryonic antigen mRNA analysis detects micrometastatic cells in blood from lung cancer patients. Uptake of recombinant iduronatesulfatase into neuronal and glial cells in vitro.

Analysis of Sanfilippo A gene mutations in a large pedigree. Species variability in platelet aggregation response to different agonists. Expression levels of the focal adhesion-associated proteins paxillin and pCAS in canine and feline mammary tumors. Adhesive properties of platelets from different animal species. Exploitation of proteomic strategies in protein structure unction studies. Isolation and characterization of Staufen-containing ribonucleoparticles from rat brain. Fusidic and helvolic acid inhibition of elongation factor 2 from the archaeon Sulfolobus solfataricus.

Sequence and structure-activity relationship of a scorpion venom toxin with nitrergic activity in rabbit corpus cavernosum. Determination of RSD in human plasma by high-performance liquid chromatography-tandem mass spectrometry using tri-deuterated RSD as internal standard: A paraoxonase gene polymorphism, PON 1 55 , as an independent risk factor for increased carotid intima-media thickness in middle-aged women.

BAG3 protein regulates cell-survival in childhood acute lymphoblastic leukemia cells. Association of obesity and central fat distribution with carotid artery wall thickening in middle-aged women. Radical-trapping activity, blood pressure, and carotid enlargement in women. Redox control of signal transduction, gene expression and cellular senescence.

Hepatitis B virus reactivation after fludarabine-based regimens for indolent non-Hodgkin lymphomas: Effect of paraformaldehyde on platelet size and on measurement of surface IgG. Human aldolase A natural mutants: Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation. Late relapse of acute promyelocytic leukemia treated with all- trans retinoic acid and chemotherapy: Molecular response to imatinib in late chronic-phase chronic myeloid leukemia.

Deletions on der 9 chromosome in adult Ph-positive acute lymphoblastic leukemia occur with a frequency similar to that observed in chronic myeloid leukemia. High-mobility group A1 proteins are overexpressed in human leukaemias. Real-time quantification of different types of bcr-abl transcript in chronic myeloid leukemia. CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy.

Acute promyelocytic leukemia after treatment for non-Hodgkin's lymphoma with drugs targeting topoisomerase II. Detection of bcr-abl transcript in chronic myelogenous leukemia patients by reverse-transcription-polymerase chain reaction and capillary electrophoresis. Recanalization of thrombosed hemodialysis shunt by venous transposition.

Trisomy 13 in a case of myelofibrosis with myeloid metaplasia with early blastic transformation. Mutation of the feh-1 gene, the Caenorhabditis elegans orthologue of mammalian Fe65, decreases the expression of two acetylcholinesterase genes. Quality assessment in cytogenetic and molecular genetic testing: Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene. Biochemical Characterization and Cloning of the Encoding Gene.

Imatinib and pegylated human recombinant interferon-alfa2b in early chronic-phase chronic myeloid leukemia. A dramatic case of early-onset familial adenomatous polyposis. Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child.

Short and highly efficient synthetic promoters for melanoma-specific gene expression. Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: Analysis of dystrophin gene deletions correlates the hinge III region of the protein with the disease severity.

Amyloid-beta protein precursor AbetaPP intracellular domain-associated protein-1 proteins bind to APP and modulate its processing in an isoform specific manner. JNK-interacting protein-1 promotes transcription of Ab protein precursor but not Ab precursor-like proteins, mechanistically different than Fe Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia.

Helper-dependent adenoviral vector-mediated long-term expression of human apolipoprotein A-I reduces atherosclerosis in apo E-deficient mice. Diverse human aldolase C gene promoter regions are required to direct specific LacZ expression in the hippocampus and Purkinje calls of transgenic mice.

Isolated elevated sweat chloride concentrations in the presence of the rare mutation SX: Several interacting genes influence the malignant hyperthermia phenotype.

Jurkat-Rott K , Mueller C. GDNF family ligand immunoreactivity in the gut of teleostan fish. Flavoridin inhibits Yersinia enterocolitica uptake into fibronectin-adherent HeLa cells. Pro-apoptotic signaling pathway activated by echistatin in GD25 cells. Identification and characterization of structural domains of Human ERp Fibromodulin gene transcription is induced by ultraviolet irradiation, and its regulation is impaired in senescent human fibroblasts.

Rapamycin stimulates apoptosis of Childhood acute lymphoblastic leukemia cells. Cup ia a nucleo-cytoplasmic shuttling protein that interacts with the eukaryotic translation initiation factor 4E to modulate Drosophila ovary development. Functional analysis of the promoter of the mitochondrial phosphate carrier human gene: An adult Sanfilippo type A patient with homozygous mutation RP in the sulfamidase gene. Modulation of chondrocyte adhesion to collagen by echistatin.

Paraoxonase and superoxide dismutase gene polymorphisms and noise-induced hearing loss. Alternative splicing and nonsense-mediated mRNA decay regulate mammalian ribosomal gene expression. Effect of high-density lipoprotein cholesterol levels on carotid artery geometry in a Mediterranean female population. Y-chromosome short tandem repeat STR haplotypes in a Campania population sample.

The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: Archaeal elongation factor 1 from Sulfolobus solfataricus interacts with the eubacterial antibiotic GEA. PEGylated helper-dependent adenoviral vectors: AKT participates in endothelial dysfunction in hypertension. Site-directed mutagenesis mediated by a single polymerase chain reaction product.

High attenuation and immunogenicity of a simian immunodeficiency virus expressing a proteolysis-resistant inhibitor of NF-kappa B. Randomized comparison of power Doppler ultrasound-directed excisional biopsy with standard excisional biopsy for the characterization of lymphadenopathies in patients with suspected lymphoma.

Genes transcriptionally modulated by interferon alpha2a correlate with the cytokine activity. Growth factor receptor-bound protein 2 interaction with the tyrosine-phosphorylated tail of amyloid beta precursor protein is mediated by its Src homology 2 domain.

Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase. Systematic analysis of human kinase genes: Timed mutation and cell-fate mapping reveal reiterated roles of Tbx1 during embryogenesis, and a crucial function during segmentation of the pharyngeal system via regulation of endoderm expansion.

Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1. Dissecting contiguous gene defects: Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract. Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.

Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Generating and modifying DiGeorge syndrome-like phenotypes in model organisms: Phenotypic expression of genotype-phenotype correlation in cystic fibrosis patients carrying the del22 mutation. Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations.

Butyrate as an effective treatment of congenital chloride diarrhea. Molecular genotyping of the Italian cohort of patients with hemophilia B. Microcytic anemia and hepatic iron overload in a child with compound heterozygous mutations in DMT1.

Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1. A second locus mapping to 2q for familial pseudohyperkalaemia. Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.

BAG3 protein regulates stress-induced apoptosis in normal and neoplastic leukocytes. NF-kB regulates inflammatory cell apoptosis and phagocytosis in rat carrageenin-sponge implant model.

Genetic typing of Corallium rubrum. Crystallization and preliminary X-ray crystallographic analysis of the Sulfolobus solfataricus nucleotide-exchange factor 1beta. Artemin-like immunoreactivity in the zebrafish, Danio rerio. Interaction of archaeal translation elongation factors with eubacterial protein synthesis inhibitors. Post-translational modifications of translation elongation factor 1A in apoptosis induced by IFNalpha.

Comprehensive cystic fibrosis mutation epidemiology and haplotype characterization in a southern Italian population. Expression and intracellular localization of Pyk2 in normal and v-src transformed chicken epiphyseal chondrocytes. AROS is involved in adaptive response to oxidative stress. Transcription regulation in NIH3T3 cell clones resistant to diethylmaleate-induced oxidative stress and apoptosis.

The 3'-untranslated region directs ribosomal protein-encoding mRNAs to specific cytoplasmic regions. Differences in methylation patterns in the methylation boundary region of IDS gene in Hunter syndrome patients: Comparison of the TaqMan and LightCycler systems in pharmacogenetic testing: Hereditary fructose intolerance and celiac disease: Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors.

Selective Rac-1 inhibition protects from diabetes-induced vascular injury. Cardiac troponin T and amino-terminal pro-natriuretic peptide concentrations in fetuses in the second trimester and in healthy neonates.

ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: Adult T-cell acute lymphoblastic leukemia: Comparison between patients with Philadelphia-positive chronic phase chronic myeloid leukemia who obtained a complete cytogenetic response within 1 year of imatinib therapy and those who achieved such a response after 12 months of treatment.

Nitric oxide-induced endoplasmic reticulum stress activates the expression of cargo receptor proteins and alters the glycoprotein transport to the Golgi complex. Achieving a major molecular response at the time of a complete cytogenetic response CCgR predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients.

Immunohistochemistry predicts nucleophosmin NPM mutations in acute myeloid leukemia. Estimation of bulky lymph nodes by power Doppler ultrasound scanning in patients with Hodgkin's lymphoma: Retinoic acid induces p27Kip1 nuclear accumulation by modulating its phosphorylation.

Plakoglobin is differentially expressed in alveolar and embryonal rhabdomyosarcoma and is regulated by DNA methylation and histone acetylation. Psychrophilic superoxide dismutase from Pseudoalteromonas haloplanktis: A larger spectrum of intragenic STRs improves linkage analysis and localization of intragenic recombination detection in the dystrophin gene: Local administration of WIN 55, reduces chronic granuloma-associated angiogenesis in rat by inhibiting NF-kappaB activation.

Elevated expression and polymorphisms of SOCS3 influence patient response to antiviral therapy in chronic hepatitis C.

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Involvement of the Arg in the active site of human IL Analysis of transglutaminase protein substrates by functional proteomics. Multiple binding mode of reversible synthetic thrombin inhibitors. Natural History of Acute Pancreatitis:

In vivo dosimetry to assess fetal dose. Ten-year experience at the European Institute of Oncology in Milan. A Randomized Multicenter Trial. Assessment of early continence after reconstruction of the periprostatic tissues in patients undergoing computer assisted robotic prostatectomy: The survival impact of the choice of surgical procedure after ipsilateral breast cancer recurrence. A Randomized Controlled Trial. A case control study.

Expanding the role of hepatic resection in the age of multimodal therapy. Are We Approaching an Answer? Efficacy and Toxicity Data from a Retrospective Study. Central Venous Catheters access, care, diagnosis and therapy of complications. ESMO clinical recommendations for diagnosis, treatment and follow-up.

Workflow della Ricerca 2. A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM, a novel Aurora kinase inhibitor. Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization. Epigenetic therapies in haematological malignancies: Epigenomic profiling of cancer cells.

Ethics report on interspecies somatic cell nuclear transfer research. Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells. Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation.

K-ras status in squamous cell anal carcinoma SCC: Mitochondria and vascular pathology. Mitochondrial pathways for ROS formation and myocardial injury: Protein phosphatases take the mitotic stage. Systems-wide analysis of a phosphatase knock down by quantitative proteomics and phosphoproteomics. Tandem repeats modify the structure of human genes hosted in segmental duplications.

The future therapeutic potential of histone demethylases: The gene prognosis-signature predicts disease outcome in breast cancer patients with positive lymph nodes in an independent validation study.

Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab. What to do with the Grail now that we have it? A novel t 7;13 p12;q33 approximately q34 in AML-M2. Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma MPM cells. Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks.

Fragment-based identification of Hsp90 inhibitors. Heat-shock factor 1 controls genome-wide acetylation in heat-shocked cells. Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer. Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Isolation and characterization of DUSP11, a novel p53 target gene.

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. P66Shc signals to age. Rai acts as a negative regulator of autoimmunity by inhibiting antigen receptor signaling and lymphocyte activation. The Aurora B kinase activity is required for the maintenance of the differentiated state of murine myoblasts. The life and miracles of kinetochores. Two modes of transcriptional activation at native promoters by NF-kappaB p When sirtuins and NF-kappaB collide.

Awaking stem cells from dormancy: Fractal growth of tumors and other cellular populations: Human intestinal epithelial cells promote the differentiation of tolerogenic dendritic cells. Molecular and functional analysis of the stem cell compartment of chronic myelogenous leukemia reveals the presence of a CD cell population with intrinsic resistance to imatinib.

Pathological definition of triple negative breast cancer. Redundant function of retinoic acid receptor isoforms in leukemogenesis unravels a prominent function of genome topology and architecture in the selection of mutagenic events in cancer. The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

A reevaluation of the clinical significance of histological subtyping of non-small-cell lung carcinoma: A risk score to predict disease-free survival in patients not achieving a pathological complete remission after preoperative chemotherapy for breast cancer. Alterations of ubiquitin ligases in human cancer and their association with the natural history of the tumor. Are surveillance procedures of clinical benefit for patients treated for ovarian cancer? Biomarkers for risk assessment and prevention of breast cancer.

Central nervous system metastases in a cohort of metastatic breast cancer patients treated with trastuzumab. Circulating melanoma cells and distant metastasis-free survival in stage III melanoma patients with or without adjuvant interferon treatment EORTC side study.

Communication skills and raising awareness in clinical practice: Distribution of human papillomavirus genotypes in invasive cervical cancer in Italy: Epidemiology of pancreatic cancer: Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor BDNF.

For the sake of clarity about pT4 category of colorectal cancer. Hepatitis C virus genotype 1b as a risk factor for hepatocellular carcinoma development: Improved histologic and clinicopathologic criteria for prognostic evaluation of pancreatic endocrine tumors. Increasing steroid hormone receptors expression defines breast cancer subtypes non responsive to preoperative chemotherapy.

Information-related changes in contact patterns may trigger oscillations in the endemic prevalence of infectious diseases. Integrating molecular profiling, histological type and other variables: Invasive ductal carcinoma of the breast with the "triple-negative" phenotype: Lack of prognostic significance of "classic" lobular breast carcinoma: Natural History of Acute Pancreatitis: Review and meta-analysis on Vitamin D Receptor polymorphisms and cancer risk.

Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy. The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells.

The changing character of acute pancreatitis: The Gene expression Grade Index: The Harmless Acute Pancreatitis Score: Tumor deposits are encountered in advanced colorectal cancer and other adenocarcinomas: Which factors affect pulmonary function after lung metastasectomy?

Before they were gut dendritic cells. Best choice of central venous insertion site for the prevention of catheter-related complications in adult patients who need cancer therapy: Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG trial.

Bone Quality Test BQT scores of fingernails in postmenopausal patients treated with adjuvant letrozole or tamoxifen for early breast cancer.

Clinical and pharmacological phase I evaluation of exherin ADH-1 , a selective anti n-cadherin peptide in patients with n-cadherin expressing solid tumours. Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: Dendritic cells in intestinal homeostasis and disease.

Erlotinib combined with cyclosporine in a liver-transplant recipient with epidermal growth factor receptor-mutated non-small cell lung cancer. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. Gemcitabine and pemetrexed combination: HSPPC vaccine in metastatic melanoma patients: Immunizing against breast cancer: Infusional fluorouracil, epirubicin, and cisplatin followed by weekly paclitaxel plus bevacizumab in locally advanced breast cancer with unfavorable prognostic features.

International guidelines for management of metastatic breast cancer: Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning. Investigations after adjuvant therapy. Is adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? Is chemotherapy necessary for premenopausal women with lower-risk node-positive, endocrine responsive breast cancer?

Is there a role for 'modified VAD' in the treatment of multiple myeloma? Minimal axillary lymph node involvement in breast cancer has different prognostic implications according to the staging procedure. Molecular target therapy for gastroenteropancreatic endocrine tumours: Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: Patterns of recurrence of early breast cancer according to estrogen receptor status: Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours.

Properties of the elongation factor 1 alpha in the thermoacidophilic archaebacterium Sulfolobus solfataricus [published erratum appears in Eur J Biochem Dec 18; 3: Resistance of archaebacterial aEF-1 alpha. GDP against denaturation by heat and urea. Archaebacterial elongation factor 1 alpha carries the catalytic site for GTP hydrolysis.

Purification and characterization of NADH oxidase from the archaea Sulfolobus acidocaldarius and Sulfolobus solfataricus. Properties of truncated forms of the elongation factor 1alpha from the archaeon Sulfolobus solfataricus.

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Post-transcriptional control of negative acute phase genes by transforming growth factor beta. Effect of TGF beta on liver genes expression. Reference intervals for eight modified nucleosides in serum in a healthy population from Italy and the United States. Serum pseudouridine in the diagnosis of acute leukaemias and as a novel prognostic indicator in acute lymphoblastic leukaemia.

Estimation of extremely low amounts of single mRNAs by quantitative noncompetitive reverse transcription--polymerase chain reaction assays in biological specimens from normal and neoplastic cells. Allele frequency distributions at several variable number of tandem repeat VNTR and short tandem repeat STR loci in a restricted Caucasian population from south Italy and their evaluation for paternity and forensic use. A quantitative polymerase chain reaction PCR assay completely discriminates between Duchenne and Becker muscular dystrophy deletion carriers and normal females.

Novel mutations and structural implications in R-type pyruvate kinase- deficient patients from Southern Italy. A 5' regulatory sequence containing two Ets motifs controls the expression of the Wiskott-Aldrich syndrome protein WASP gene in human hematopoietic cells. Progressive deficiencies in blood T cells associated with a 10p interstitial deletion. Combined immunodeficiency phenotype associated with inappropriate spontaneous and activation-induced apoptosis. PCR analysis of the H ferritin multigene family reveals the existence of two classes of processed pseudogenes.

Genotoxic potency of monofunctional alkylating agents in E. Spontaneous and mutagen-mediated amplification of a neo gene integrated at different genomic sites in rat 2 fibroblasts.

The human immunodeficiency virus type 1 long terminal repeat is activated by monofunctional and bifunctional DNA alkylating agents in human lymphocytes. Molecular, functional and structural properties of an archaebacterial elongation factor 2. Properties of the purified elongation factor 2 in the thermoacidophilic archaebacterium Sulfolobus solfataricus. Studies on the polypeptide elongation factor 2 from Sulfolobus solfataricus. Interaction with guanosine nucleotides and GTPase activity stimulated by ribosomes.

Archaeal elongation factor 1 beta is a dimer. Primary structure, molecular and biochemical properties. The site for GTP hydrolysis on the archaeal elongation factor 2 is unmasked by aliphatic alcohols.

The effect of ribosome-inactivating proteins on the ribosome from the hyperthermophilic archaeon Sulfolobus solfataricus. Inositol-specific phospholipase D activity in health and disease. Assignment of human aldolase C gene to chromosome 17, region cenq Defect of interleukin-2 production and T cell proliferation in atopic patients: Regulation of NF-kappa B nuclear activity in peripheral blood mononuclear cells: Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells.

Immortalization of a cell line showing some characteristics of the oligodendrocyte phenotype. Glyceraldehydephosphate dehydrogenase in the hyperthermophilic archaeon Sulfolobus solfataricus: Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein. Electrophoretic behavior and partial characterization of disease- associated serum forms of gamma-glutamyltransferase. Evaluation of pancreatic amylase immunoassay in acute pancreatitis.

Diagnostic value of various serum antibodies detected by diverse methods in childhood celiac disease. Problems and perspectives of clinical biochemistry training, and the example of Italy. Multivariate discriminant analysis of biochemical parameters for the differentiation of clinically confounding liver diseases. The molecular basis of hereditary fructose intolerance in Italian children.

Molecular basis of hereditary fructose intolerance in Italy: Dystrophinopathy in a young boy with Klinefelter's syndrome. Expression of an exogenous interleukin 6 gene in human Epstein Barr virus B cells confers growth advantage and in vivo tumorigenicity.

Induction of tumorigenicity and plasmacytoid differentiation in EBV-B cells by expression of exogenous interleukin-6 or IL-6 receptor genes. Epstein-Barr virus nuclear antigen 2 transactivates the long terminal repeat of human immunodeficiency virus type 1.

The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein. Three novel germline mutations in the adenomatous polyposis coli gene. Interleukinbeta modulation of prolactin secretion from rat anterior pituitary cells: Simultaneous occurrence of tetrasomy 21 and trisomy 8 in a patient with early blastic metamorphosis of chronic myeloproliferative disorder.

Expression of the neuron-specific FE65 gene marks the development of embryo ganglionic derivatives. The familial adenomatous polyposis region exhibits many different haplotypes. Immunosuppressive activity of bovine seminal RNase on T-cell proliferation. UN-1, a murine monoclonal antibody recognizing a human thymocyte undescribed antigen. Analysis of peripheral blood normal and malignant cells with the novel murine monoclonal antibody UN2.

UN1, a murine monoclonal antibody recognizing a novel human thymic antigen. A novel monoclonal antibody recognizing human thymocytes and B-cell chronic lymphocytic leukemia cells [published erratum appears in Immunol Lett Apr;40 1: CD69 expression on primitive progenitor cells and hematopoietic malignancies.

CD36 is rapidly and transiently upregulated on phytohemagglutinin PHA - stimulated peripheral blood lymphocytes. Analysis by a new monoclonal antibody UN7. T-cell malignancies with mature phenotypes: Lymphocyte proliferative response to mitogenic monoclonal antibodies in systemic sclerosis. Evidence for unresponsiveness to murine monoclonal antibodies of IgG1 isotype.

DNA-binding protein Pur alpha and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter. Enhancement by cysteinyl thiols of acetyltransferase-mediated, but not of sulfotransferase-mediated, binding of a pyrolysate-derived N-hydroxyarylamine, 2-hydroxyaminomethyldipyrido[1,2-a: Collaborative study of the molecular epidemiology of Tay-Sachs disease in Europe.

Serum beta 2-microglobulin levels and p24 antigen, lymphocyte depletion and disease progression in human immunodeficiency virus infection. Characterization of oxidative and reductive metabolism in vitro of nitrofluoranthenes by rat liver enzymes. Metal-ion catalyzed oxidation affects fibrinogen activity on platelet aggregation and adhesion.

The intermediate compartment between endoplasmic reticulum and Golgi complex in mammalian cells. Analysis of metal-regulated metallothionein and heat shock gene expression in HeLa-derived cadmium-resistant cells. Bone marrow transplantation in Hunter syndrome. Cloning and characterization of the cDNA for the murine iduronate sulfatase gene.

Expression of the two iduronatesulfatase cDNAs. Characterization of hemoglobin lepore variants by advanced mass-spectrometric procedures. Haemostasis unbalance in Pugh-scored liver cirrhosis: Evidence of a cold immunoglobulin M autoantibody against kD platelet glycoprotein in a case of EDTA-dependent pseudothrombocytopenia. Preliminary molecular analysis of a case of feline mucopolysaccharidosis VI.

Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex. In vivo accumulation of 8-hydroxy-2'-deoxyguanosine in DNA correlates with release of reactive oxygen species in Fanconi's anaemia families.

In vitro correction of iduronatesulfatase deficiency by adenovirus-mediated gene transfer. Animal models for lysosomal storage diseases: Cell-to-cell contact between normal fibroblasts and lymphoblasts deficient in lysosomal enzymes. Biochemical diagnosis of mucopolysaccharidoses: Identification of molecular defects in Italian Sanfilippo A patients including 13 novel mutations.

Isolation of a cDNA encoding a metal response element binding protein using a novel expression cloning procedure: Two novel R C; TD and two repeat missense mutations in the protein C gene associated with venous thrombosis in six kindreds. A nuclear factor binds to the metal regulatory elements of the mouse gene encoding metallothionein-I.

Rational design of true hirudin mimetics: Immunocytochemical analysis of the transfer of vesicular stomatitis virus G glycoprotein from the intermediate compartment to the Golgi complex.

Morphological analysis of the transfer of VSV ts G glycoprotein from the endoplasmic reticulum to the intermediate compartment in vero cells. Surface distribution and partition during freeze-fracture of CD8 antigens on human lymphocytes and on epithelial transfected cells. Effect of rat liver cytosolic enzymes and cofactors on mutagenicity of 1-aminonitropyrene. Interactions of nuclear proteins from uninduced, induced and superinduced HeLa cells with metal regulatory elements MRE3 and 4 of the human metallothionein IIa-encoding gene.

Synthesis of rhodanese in Hep 3B cells. The iduronate sulfatase gene: Post-translational processing of an O-glycosylated protein, the human CD8 glycoprotein, during the intracellular transport to the plasma membrane. Biosynthesis and oligosaccharide structure of human CD8 glycoprotein expressed in a rat epithelial cell line.

Dynamics of transmembrane proteins during Sindbis virus budding. Collagen expression in quail embryo chondrocytes treated with retinoic acid. Alpha 2 I collagen gene expression is up-regulated in quail chondrocytes pretreated with retinoic acid. Enhancement of tissue lipoperoxidation in propanil-treated rats. Amino acid sequence and molecular modelling of glycoprotein IIb-IIIa and fibronectin receptor iso-antagonists from Trimeresurus elegans venom. Glycosylation and maturation rate of membrane and secretory forms of human CD8 alpha glycoprotein.

Implications in the activation of T-lymphocytes. Sanfilippo syndrome type D in two adolescent sisters. Echistatin inhibits the adhesion of murine melanoma cells to extracellular matrix components. Echistatin induces decrease of ppFAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells. Echistatin inhibits pp72syk and ppFAK phosphorylation in fibrinogen-adherent platelets.

Anchorage-dependent surface distribution and partition during freeze-fracture of viral transmembrane glycoproteins. Effect of ATP depletion and DTT on the transport of membrane proteins from the endoplasmic reticulum and the intermediate compartment to the Golgi complex. Opposite polarity of virus budding and of viral envelope glycoprotein distribution in epithelial cells derived from different tissues.

The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode. Species-dependent specificity of platelet aggregation inhibitors from snake venoms. The carcinogenic mycotoxin fumonisin B1 inhibits integrin-mediated cell-matrix adhesion. From natural to synthetic multisite thrombin inhibitors. Prenatal diagnosis of Sanfilippo type A syndrome in a family with S66W mutant allele. Bone marrow transplantation in a Hunter patient with PH mutation.

Cell fractionation analysis of human CD8 glycoprotein transport between endoplasmic reticulum, intermediate compartment and Golgi complex in tissue culture. Tissue-transglutaminase expression in quail epiphyseal chondrocytes.

A chimeric elongation factor containing the putative guanine nucleotide binding domain of archaeal EF-1 alpha and the M and C domains of eubacterial E. The interaction between the archaeal elongation factor 1a and its nucleotide exchange factor 1b. Regulation of cell survival in CDinduced T cell apoptosis: CD40 and B chronic lymphocytic leukemia cell response to fluderabine: Sequence and analysis of chromosome 4 of the plant Arabidopsis Thaliana.

Changes in tissue transglutaminase activity and expression during retinoic acid-induced growth arrest and apoptosis in primary cultures of human epithelial prostate cells. Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein. A novel case of multiple endocrine neoplasia type 2 associated with two de novo mutations of the RET protooncogene.

Pro12Ala substitution in the peroxisome proliferator activated receptor-gamma 2 is not associated with type 2 diabetes.

The type and the localization of cAMP-dependent protin kinase regulate trasmission of cAMP signals to the nucleus in cortical and cerebellar granule. Thrombin mutants with altered enzymatic activity have an altered mitogenic activity on NIH3T3 cells and are inefficient modulators of rat cortical astrocyte stellation.

A case of discordance between genotype and phenotype in a malignant hyperthemia family. IgA antibodies to tissue transglutaminase: Efficiency of two different nine-loci short tandem repeat systems for DNA typing purposes.

Novel six-nucleotide deletion in the hepatic fructose-1,6-bisphosphate aldolase gene in a patient with hereditary fructose intolerance and enzyme structure-function implications. Serum gamma-glutamyltransferase isoform complexed to LDL in the diagnosis of small hepatocellular carcinoma. Detection of five rare cystic fibrosis mutations peculiar to Southern Italy: Familial adenomatous polyposis coli: PKC-dependent phosphorylation of the p97 repressor regulates the transcription of aldolase A L-type promoter.

Stem cell factor is localized in released form, and cleaved by human mast cells. Dual control of C-reactive protein gene expression by interleukin-1 and interleukin Comparison of seven serum assays on four automatic analysers. Characterization of the induction of rat hepatic microsomal drug-metabolizing enzymes by 1-nitropyrene metabolites, 1-aminopyrene and N-acetylaminopyrene. Palmitylation of viral membrane glycoproteins takes place after exit from the Endoplasmic Reticulum.

Biosynthesis, membrane translocation, and surface expression of sindbis virus E1 glycoprotein. Biochemical diagnosis of Hunter syndrome on Epstein-Barr virus transformed lymphoblastoid cell lines. Mapping of the gene TCF2 coding for the transcription factor LFB3 to human chromosome 17 by polymerase chain reaction. Transcription of the promoter of the rat NF-l gene depends un the integrity of an Sp1 recognition site. Extinction of retinol-binding protein gene expression in somatic cell-hybrids: Identification of the target sequences.

Regulation of the human C-reactive protein gene, a major marker of inflammation and cancer. Promoters and inhibitors of calcium urolithiasis in children. Metabolic activation of dinitropyrenes by human liver fractions. Long term antihypertensive effect of magnesium supplementation in primary hypertension. Single-step purification and structural characterization of human interleukin-6 produced in Escherichia coli from a T7 RNA polymerase expression vector.

Regulation and expression of type V Tartrate-resistant acid phosphatase in human mononuclear phagocytes. Correlates of high-density lipoprotein cholesterol in a sample of healthy workers. Serum selenium and coronary heart disease risk factors in southern Italian men. Early macrophage infiltration in Mice treated with low-dose streptozocin decreases islet suproxide dismutase levels: Superoxide dismutase in low-dose-streptozocin-treated mice.

Vitamin A intake and in vivo expression of the genes involved in retinol transport. Biologically active recombinant prothrombin and antithrombin III expressed in a human hepatoma vaccinia virus system.

Reversible inhibition of thyroid-specific trans-acting factor by Ras. Effect of avarol, avarone and nine their natural and synthetic derivatives on drug-metabolizing enzymes. Tubular function by lithium clearance, plasma amino acids and hormones following a meat meal in childhood.

Expression of type X collagen is transiently stimulated in redifferentiating chondrocytes pretreated with retinoic acid. Identification of regulatory residues of the yeast adenylyl cyclase. Role of glycine as a pivot point during the transition from the inactive to the active form of the yeast Ras2 protein. A consensus view on the use of immunodeficient mice in immunology and oncology.

Extinction of a-1 antitrypsin gene expression in somatic cell hybrids: Control of human coagulation by recombinant serine proteases. Blood clotting is activated by recombinant factor XII deleted of five regulatory domains.

Per-rectal portal scintigraphy with technetiumm pertechnetate for the early diagnosis of cirrhosis in patients with chronic hepatitis. Transcription factors of liver-specific genes. Calcium and blood pressure in a sample of male workers.

Hemodialysis related induction of interleukin-6 production by peripheral blood mononuclear cells. Idiopathic neonatal hepatitis in one DNA fingerprint identical twin. Effect of avarol and avarone on in vitro-induced microsomal lipid peroxidation. Glucagon-independent renal hyperaemia and hyperfiltration after an oral protein load in child a liver cirrhosis. Renal handling of sodium after an oral protein load in adult humans.

Long-term magnesium supplementation in essential hypertension. Structural characterization of a biologically active human lipocortin 1 expressed in Escherichia coli. Can overnight urine replace hour urine collection to measure urinary calcium in epidemiologic studies? Human L7a ribosomal protein: Cellular retinoic-acid-binding-protein mRNA expression in the cells of the rat seminiferous tubules and their regulation by retinoids.

Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression.

Diagnostic and discriminatory efficiency of eight serum modified nucleosides in HIV infection and in AT-Risk subjects. A method for the assay of phosphatidylinositol-specific phospholipase D activity in serum. Identification of a binding site for the human immunodeficiency virus type I nucleocapsid protein.

Extinction of insulin-like growth factor II gene expression in intratypic hibrids of rat liver cells. Nucleotide sequence and molecular evolution of the gene coding for glyceraldehydephosphate dehydrogenase in the thermoacidophilic archaebacterium Sulfolohus solfataricus. T cell growth-promoting activity of JFN-y: Rapid and efficient resolution of parentage by amplification of short tandem rcpeats.

High-resolution solution structure of the oligomerization domain of p53 by multidimensional NMR. The carboxy-terminal serine phosphorylation site of human p53 Fis not required for wild-type activities.

Lipids of human gastric mucosa: An increase in superoxide dismutase counteracts islet vascular alterations in low-dose streptozocin-treated mice. Arylation of sulfhydryl groups in vitro by the naturally occurring sesquiterpenoid benzoquinone avarone.

Cristallization of a hyperthermophilic archaeal elongation factor 1a. The effects of intra-articular administration of hyaluronic acid on osteoarthritis of the Knee: Differential regulation of the expression of interleukin-2 receptor y-chain during the in vitro differentiation of human myeloid cells.

Oxidative structural modifications of low density lipoprotein in homozygous familial hypercholesterolemia. Direct detection of proviral-gag-segment of human immunodeficiency virus in peripheral blood lymphocytes by colorimetric PCR assay as a Clinical Laboratory tool applied to different at-risk populations.

Superoxide dismutase in the nonobese diabetic NOD mouse: Detection of an antigenic marker expressed by peripheral blood monocytes and platelets by a new monoclonal antibody, UN8. The role of cell adhesion in Retinoic acid-induced modulation of chondrocytes phenotype. Interaction between archaeal elongation factors lb and la.

A mutation in the RET proto-oncogene in Hirschsprung's disease affects the tyrosine kinase activity associated with multiple endocrine neoplasia type 2A and 2B. Complete phenotypic and genotypic lineage switch in a Philadelphia chromosome-positive acute lymphoblastic leukemia. Inhibition of human platelet adhesion to immobilized extracellular matrix components by disintegrins.

Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction. Aspartate aminotransferase from the thermophilic bacterium Thermus aquaticus YT Functional characterisation and stability. The effect of low density lipoprotein fatty acid compoosition on copper-induced peroxidation: Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli. Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle-and developmentally regulated promoter.

Proteolysis of the exodomain of recombinant protease-activated receptors: Oxalomalate, a competitive inhibitor of aconitase, modulates the RNA-binding activity of iron-regulatory proteins. Over expression of H ferritin and upregulation of iron regulatory protein genes during differentiation of 3T3-L1 pre-adipocytes.

Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis. Protein engineering on enzymes of the peptide elongation cycle in Sulfolobus solfataricus. Discrimination between Celiac and other gastrointestial disorders in childhood by rapid human lymphocyte antigen typing. Germime and somatic mutations of the RET proto-oncogene in apparently sporadic medullary thyroid carcinomas.

Mutations in the extracellular domain cause RET loss of function by a dominant negative mechanism. Echistatin inhibits Lewis lung carcinoma cell-matrix adhesion in vitro and experimental metastasis in vivo.

Functional characterization of elegantin isoform, RGD-polypeptides isolated from the venom of Trimeresurus elegans. Stable expression and purification of a secreted human recombinant prethrombin-2 and its activation to thrombin.

Mutations among Italian Mucopolysaccharidosis type I patients. Detection of four novel mutations in the iduronatesulfatase gene. Two novel mutations of the arylsulfatase B gene in two Italian patients with severe form of mucopolysaccharidosis.

Retynil esters hydrolysis and retinol efflux from BFC-1beta adipocytes. Retinoic acid receptors a, b and g and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer. A novel point mutation in the intracellular domain of the RET proto-oncogene in a family with medullary thyroid carcinoma. Identification of two mutations within the transglutaminase 1 gene in patients with lamellar ichthyosis. Microsatellite instability in patients with early onset of colorectal cancer.

Constitutive and IL-6 induced nuclear factors that interact with the human C-reactive protein promoter. Internal deletion of human interleukin Internal deletion of amino acids of human interleukin-6 IL-6 differentially affect bioactivity and folding of the protein. Involvement of the Arg in the active site of human IL Synergistic stimulation of interleukin-6 release and gene expression by phorbol esters and interleukin-1 in rat cortical astrocytes: Two types of zinc fingers are required for dimerization of the serendipity delta transcriptional activator.

Transcriptional control of gene expression in hepatic cells. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Psychrophilic elongation factor Tu from the Antarctic Moraxella sp. Expression of five iduronatesulfatase site-directed mutations. Echistatin inhibits ppFAK autophosphorylation paxillin, phosphorylation and ppFAK-paxillin interaction in fibronectin-adherent melanoma cells.

Molecular defects in the alfa-N-acetylglucosaminidase gene in Italian Sanfilippo type B patients. The beta-amyloid precursor protein APP functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation. Identification of a novel mutation in the ryanodine receptor gene RYR1 in a malignant hyperthermia italian family.

Functional and molecular modelling studies of two hereditary fructose intolerance-causing mutations at arginine in human liver aldolase. Quantitative analysis of aldolase A mRNA in liver discriminates between hepatocellular carcinoma and cirrhosis.

Prenatal diagnosis of cystic fibrosis: Genetic history of cystic fibrosis mutations in Italy. Evidence for a recessive inheritance of Turcot's syndrome caused by a compound heterozygous mutation within the PMS2 gene. H2O2 activity on platelet adhesion to fibrinogen and protein tyrosine phosphorylation.

Immobilised echistatin promotes platelet adhesion and protein tyrosine phosphorylation. Retinol and retinol-binding protein: Identification of a novel retinoic acid response element in the promoter region of the retinol-binding protein gene.

Retinoids regulate expression of the retinol-binding protein in hepathoma cells in culture. The archaeal elongation factor 1alpha bound to GTP forms a ternary complex with eubacterial and eukaryal aminoacyl-tRNA. A new determinant of endoplasmic reticulum localization is contained in the juxtamembrane region of hepatitis C virus glycoprotein E1. Zinc transport and metallothionein secretion in the intestinal human cell line Caco Sequence polymorphisms in the apo a gene associated with specific levels of Lp a in plasma.

Rapid genotyping of the low density lipoprotein receptor knock-out mice using a polymerase chain reaction method. Sequence microheterogeneity in the apolipoprotein a gene repeats and the relationship to plasma Lp a levels. Plasma lipoprotein a levels in subjects attending a metabolic ward. Discrimination between individuals with and without a history of ischemic stroke.

Thrombogenic mechanisms in hyperhomocysteinemia. A simple and rapid purification procedure minimizes spontaneous oxidative modifications of low density lipoprotein and lipoprotein a. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.

Influence of cardiovascular risk factors between angiotensin converting enzyme-gene polymorphism and blood pressure in arterial hypertension. Retinoblastoma protein dephosphorylation is an early event of cellular response to prooxidant conditions. Type V Acid Phosphatase: Macroenzyme investigation and monitoring in children with persistent increase of aspartate aminotransferase of unexplained origin. Occurrence of the same peroxidative compounds in low density lipoprotein and in atherosclerotic lesions from a homozygous familial hypercholesterolemic patient: Automated enzymatic determination of urinary nitrates excrection: Increased low-density lipoprotein peroxidation in elderly men.

Comparative bioavailability of two sertraline tablet formulations in healthy human volunteers after a single dose administration. Randomized, double-blind, placebo-controlled study of arginine supplemetation in chronic renal failure.

Biochemical characterization of two crotamine isoforms isolated by a single step RP-HPLC from Crotalus durissus terrificus South American rattlesnake venom and their action on insulin secrection by pancreatic islets. Serum lipids and apolipoproteins in children with Smith-Lemli-Opitz syndrome. Smith-Lemli-Opitz syndrome with extremely low plasma cholesterol. Progress in Arabidopsis genome sequencing and functional genomics. Phenylmethanesulfonyl fluoride inactivates an archaeal superoxide dismutase by chemical modification of a specific tyrosine residue Cloning, sequencing and expression of the gene coding for Sulfolobus solfataricus superoxide dismutase.

Liver expression in cystic fibrosis could be modulated by genetic factors different from the cystic fibrosis transmembrane regulator genotype. The molecular basis of familial adenomatous polyposis in 20 families from Campania: The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene.

Transglutaminase 1 gene mutations in italian patients with autosomal recessive lamellar ichthyosis. The crystal structure of Sulfolobus solfataricus elongation factor 1 alpha in complex with GDP reveals novel features in nucleotide binding and exchange. Multivariate discriminant function based on six biochemical markers in blood can predict the cirrhotic evolution of chronic hepatitis. Site-specific atherosclerotic plaques in the carotid arteries of middle-aged women from southern Italy: Salts induce structural changes in elongation factor 1 alpha from the hyperthermophilic archaeon Sulfolobus solfataricus: Phenotype-Genotype correlations in an extended family with adenomatous coli and an unusual APC gene mutation.

Protection of rhesus macaques against disease progression from pathogenic SHIV Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein. Predictive value of Epstein-Barr virus genome copy number and BZLF1 expression in blood lymphocytes of transplant recipients at risk for lymphoproliferative disease. Extraneurologic symptoms as presenting signs of Sanfilippo disease. The effect of four mutations on the expression of iduronatesulfatase in mucopolysaccharidosis type II.

The human homologue of the mouse Surf5 gene encodes multiple alternatively spliced transcripts. Generation of helper-dependent adenoviral vectors by homologous recombination. An Alternative model of H ferritin promoter transactivation by c-Jun. A continuous line of chick embryo cells derived from a chondrocyte culture transformed with RSV.

The podosomes of RSV transformed chondrocytes show a peculiar ultrastructural organization. Association of impaired glucose homeostasis with preclinical carotid atherosclerosis in women: The first large population based twin study of coeliac disease. Serum oxidative and antioxidant parameters in a group of Italian patients with age-related maculopathy.

Stage-specific gene expression in early differentiating oligodendrocytes. Protein synthesis in the extreme thermophilic archaeon Sulfolobus solfataricus: Measurement of spleen volume by ultrasound scanning in patients with thrombocytosis: Novel deletion at the M and P promoters of the human dystrophin gene associated with a Duchenne muscular dystrophy.

In vitro acquired cellular senescence and aging-specific phenotype can be distinguished on the basis of specific mRNA expression. Genotype-Phenotype correlation in Cystic Fibrosis: The Role of Modifier Genes. Evidence for a role of the nerve growth factor receptor TrkA in tyrosine phosphorylation and processing of beta-APP. Dietary and circulating antioxidant vitamins in relation to carotid plaques in middle-aged women.

Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance. Correction of mucopolysaccharidosis type IIIB fibroblasts by lentiviral vector-mediated gene transfer.

In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors. Identification of tissue transglutaminase-reactive lysine residues in glyceraldehydephosphate dehydrogenase.

Folding and oxidation of the antibody domain CH3. Extended interactions with prothrombinase enforce affinity and specificity for its macromolecular substrate. Oxidative stress and neuroAIDS: Structural characterization of transglutaminase-catalyzed cross-linking between glyceraldehyde 3-phosphate dehydrogenase and polyglutamine repeats. Pancreatic-type ribonuclease 1 gene duplications in rat species. Molecular Diagnosis of Cystic Fibrosis: Cloning, expression and evolution of the gene encoding the elongation factor 1a from a low thermophilic Sulfolobus solfataricus strain.

Differential distribution of aldolase A and C in the human central nervous system. Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway. Recent advances in the diagnosis of malignant hyperthermia susceptibility: How confident can we be of genetic testing?

Analysis of transglutaminase protein substrates by functional proteomics. Cell-matrix interactions and the control of cell shape and differentiation in primary cultures of avian chondrocytes. Altered expression of integrins in RSV-transformed chick epiphyseal chondrocytes. Protein kinase B activation by reactive oxigen species is independent of tyrosine kinase receptor phosphorylation and requires Src activity.

Proteomics identification of Acyl-acceptor and Acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic replicons. KDEL and KKXX retrieval signals appended to the same reporter protein determine different trafficking between endoplasmic reticulum, intermediate compartment and Golgi complex.

BAG3 protein controls B-chronic lymphocytic leukemia cell apoptosis. Carcinoembryonic antigen mRNA analysis detects micrometastatic cells in blood from lung cancer patients. Uptake of recombinant iduronatesulfatase into neuronal and glial cells in vitro. Analysis of Sanfilippo A gene mutations in a large pedigree. Species variability in platelet aggregation response to different agonists. Expression levels of the focal adhesion-associated proteins paxillin and pCAS in canine and feline mammary tumors.

Adhesive properties of platelets from different animal species. Exploitation of proteomic strategies in protein structure unction studies. Isolation and characterization of Staufen-containing ribonucleoparticles from rat brain. Fusidic and helvolic acid inhibition of elongation factor 2 from the archaeon Sulfolobus solfataricus.

Sequence and structure-activity relationship of a scorpion venom toxin with nitrergic activity in rabbit corpus cavernosum.

Determination of RSD in human plasma by high-performance liquid chromatography-tandem mass spectrometry using tri-deuterated RSD as internal standard: A paraoxonase gene polymorphism, PON 1 55 , as an independent risk factor for increased carotid intima-media thickness in middle-aged women. BAG3 protein regulates cell-survival in childhood acute lymphoblastic leukemia cells.

Association of obesity and central fat distribution with carotid artery wall thickening in middle-aged women. Radical-trapping activity, blood pressure, and carotid enlargement in women.

Redox control of signal transduction, gene expression and cellular senescence. Hepatitis B virus reactivation after fludarabine-based regimens for indolent non-Hodgkin lymphomas: Effect of paraformaldehyde on platelet size and on measurement of surface IgG. Human aldolase A natural mutants: Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation.

Late relapse of acute promyelocytic leukemia treated with all- trans retinoic acid and chemotherapy: Molecular response to imatinib in late chronic-phase chronic myeloid leukemia. Deletions on der 9 chromosome in adult Ph-positive acute lymphoblastic leukemia occur with a frequency similar to that observed in chronic myeloid leukemia.

High-mobility group A1 proteins are overexpressed in human leukaemias. Real-time quantification of different types of bcr-abl transcript in chronic myeloid leukemia. CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy. Acute promyelocytic leukemia after treatment for non-Hodgkin's lymphoma with drugs targeting topoisomerase II. Detection of bcr-abl transcript in chronic myelogenous leukemia patients by reverse-transcription-polymerase chain reaction and capillary electrophoresis.

Recanalization of thrombosed hemodialysis shunt by venous transposition. Trisomy 13 in a case of myelofibrosis with myeloid metaplasia with early blastic transformation. Mutation of the feh-1 gene, the Caenorhabditis elegans orthologue of mammalian Fe65, decreases the expression of two acetylcholinesterase genes.

Quality assessment in cytogenetic and molecular genetic testing: Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene.

Biochemical Characterization and Cloning of the Encoding Gene. Imatinib and pegylated human recombinant interferon-alfa2b in early chronic-phase chronic myeloid leukemia. A dramatic case of early-onset familial adenomatous polyposis. Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET. Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child.

Short and highly efficient synthetic promoters for melanoma-specific gene expression. Inhibition of granuloma-associated angiogenesis by controlling mast cell mediator release: Analysis of dystrophin gene deletions correlates the hinge III region of the protein with the disease severity.

The gene prognosis-signature predicts disease outcome in breast cancer patients with positive lymph nodes in an independent validation study. Just what the doctor ordeerd, thankity you! Smith-Lemli-Opitz syndrome with extremely low plasma cholesterol. It brgins light into the dark!. Gene regulation by reactive oxygen species. Novel deletion at the M and P promoters of the human dystrophin gene associated with a Duchenne muscular dystrophy. Evidence of a cold immunoglobulin M autoantibody against kD platelet glycoprotein in a case of EDTA-dependent pseudothrombocytopenia. public anal danyela alves

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